Transmucosal Immediate Release Fentanyl (TIRF)
Risk Evaluation and Mitigation Strategy

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Welcome to the TIRF REMS Access Education Program for Prescribers and Pharmacists.

The TIRF REMS Access Education Program is designed to outline the key safety information critical for minimizing the risks of abuse, misuse, overdose, addiction, and serious complications associated with medication errors associated with TIRF medicines to ensure safe use.

Enrollment in the TIRF REMS Access program is necessary to prescribe and dispense TIRF medicines.

Before you can enroll in TIRF REMS Access program, you must:

  1. Review the TIRF REMS Access Education Program
  2. Successfully complete the Knowledge Assessment with a score of 100%
  3. Sign the acknowledgement statements on the enrollment form
  The TIRF REMS Access Education Program and Knowledge Assessment can be downloaded using this link.

*Prescribers writing prescriptions for inpatient use only do not need to enroll in the TIRF REMS Access program.

For assistance, please call the TIRF REMS Access program at 1-866-822-1483.